Abstract A drastic TRPA1 mutant (R919*) identified in CRAMPT syndrome patients has not been mechanistically characterized. Here. we show that the R919* mutant confers hyperactivity when co-expressed with wild type (WT) TRPA1. Using functional and biochemical assays. https://safeersappliancers.shop/product-category/zanussi-zwi71401wa-7kg-1400-rpm-built-in-washing-machine/