Can Edibles Cause Dry Mouth? Edibles like smoking or vaping can cause dry mouth or “weed cotton mouth.” THC, the brain-altering factor of cannabis, decreases saliva levels. It works alongside the endocannabinoid system. After eating edibles, THC enters the bloodstream and affects salivary glands. It leads to less saliva and dry mouth. The severity depends on the THC amount and pers... https://goodnesspsychiatryllc.com/can-cannabis-dehydrate-you/